This is a dataset with multiparametric prostate MRI applied in a test-retest setting, allowing to evaluate repeatability of the MRI-based measurements in the prostate. There is very limited data about the repeatability in mpMRI of the prostate, while such information is critical for establishing technical characteristics of mpMRI as imaging biomarker of prostate cancer.
Acquisition Protocol: Standard prostate mpMRI protocol implemented at Brigham and Women's Hospital
was used in this study. For a given patient, we aimed to maintain similar protocol settings, and
used the same scanner hardware and software configurations for both the baseline and repeat
examinations, which were acquired within 2 weeks of time. All of the imaging studies were acquired
at 3 Tesla magnet strength. Due to the scanner hardware upgrade in the middle of the study, 6 of
the patients had baseline and repeat study performed on a GE Signa HDxt platform, software release
15.0_M4A_097.a, while the remaining 7 patients were scanned on a GE Discovery MR750w, software
release DV24.0_R01_1344 (General Electric Healthcare, Milwaukee, WI). Transrectal coil within an
air-filled balloon (Medrad Inc., Warrendale, PA) was used in all imaging studies. mpMRI protocol
included T2-weighted, Diffusion Weighted (DW) (b-values of 0 and 1400 mm/s2) and Dynamic Contrast
Enhanced (DCE) sequences. Detailed acquisition parameters are listed in Table 1 of . DWI
Apparent Diffusion Coefficient (ADC) and DCE subtract maps (further referred to as SUB; computed as
the difference between the phase corresponding to the contrast bolus arrival and the baseline
phase) were generated using the scanner software.
The imaging data is accompanied by the following types of derived data: